I turned off my skimmer a month ago for fluconazole for a week, and realized that all my corals were doing better than they ever have been so I kept it off. 1 month later everything still going great. If things start to go south I can always just turn skimmer back on. I do %40 WC every week, and siphon the sand (garden eel tank) and change out sponge filters in the filtration area. That tank is mostly soft coral dominated, with some LPS like a chalice, but mostly things like toadstools, gorgonians, GSP, cloves, nepthea etc. and a red monti cap and purple stylo.