Drilling the glass is not that hard if you are careful. The main things to pay attention are low speed to avoid heating the drill bit and not much pressure on glass. I drilled 5 holes an old 6ft tank years back when I setup my 125g. I used:
- diamond coated glass drill bits, such as these,
http://www.bulkreefsupply.com/diamond-coated-glass-drill-bits.html. You'll find more in other places such as ebay & amazon, maybe even LFS.
- a battery operated drill. I like that over my plugged-in drill because it can run at a lower speed.
- plumber's putty from HD,
https://www.google.com/search?q=plumber's+putty&ie=utf-8&oe=utf-8. With this you will lay a circle "wall" on the glass around the hole to hold water to cool down the bit.
Pay extra attention to pressure & drill smooth when you reach the end. Usually you will create a small hole in one part of the drill circle & the water will start dripping through, then you need to continue cutting out the disc all around. Make sure not to press & hold the dill steady, to avoid breaking large chips in the glass.
Search online and you'll find plenty of videos and instructions. I also suggest to have some practice before: buy a piece of scrap glass from a local shop and try drilling that.
My tank glass was 3/8". Each hole took me around 20 minutes to drill, with a few short stops to stretch & relax
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For me, the thicker the glass, the easier was to drill it. It takes more time, but thicker glass is not that sensitive to pressure. I managed to crack 2 30g tanks trying to drill them after I did my 125g tank.
Also, if you need to drill from outside, you need to find a solution to lay the tank down with the back side up and horizontal. Being a semi-circle tank in front, that might be a challenge. Maybe you could drill the holes for overflow from inside as suggested earlier.